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In patients previously sensitized to specific aeroallergens, subsequent exposure induces an immunoglobulin E–mediated biochemical cascade resulting in mast cell/basophil degranulation and release of inflammatory mediators.

While an individual’s response to allergens varies, OTC therapies can offer an effective initial approach to treatment, should allergen avoidance be difficult or impractical.

About 3.5 hours after he was found with the medication bottle, he began having frequent seizures and developed a very fast heart rate and an abnormal heart rhythm.

The child had a seizure at home before emergency medical services (EMS) arrived.

Allergies often manifest after several seasonal exposures to the same set of pollens or potential allergens.

Because pharmacists are often asked to make OTC recommendations for AR relief, they must be aware of the prevalence, etiologies, and manifestations of AR, and approaches to its treatment.

PERENNIAL VERSUS SEASONAL ALLERGIC RHINITIS Perennial AR occurs year-round regardless of season and is triggered by aeroallergens such as dog/cat dander, dust mite residue, cosmetics, cockroaches, and mold.

AR is characterized by 1 or more of the following symptoms: nasal congestion, rhinorrhea, sneezing, and itching.

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